钙结合蛋白抗体
规格：1尘驳/1尘濒
英文名： Calretinin
别名： 29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; CR; CALB2_HUMAN; Calretinin.
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Calretin
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
钙结合蛋白抗体细胞定位：细胞浆 细胞膜
产物介绍：background: Calretinin is a calcium-binding protein which is abundant in auditory neurons. It belongs to the calbindin family. Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 钙结合蛋白抗体1 and calbindin2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin1. Function: Calretinin is a calcium-binding protein which is abundant in auditory neurons. Tissue Specificity: Brain. Similarity: Belongs to the calbindin family. Contains 6 EF-hand domains. Gene ID: 794 Database links: Entrez Gene: 396255 Chicken Entrez Gene: 794 Human Entrez Gene: 12308 Mouse Entrez Gene: 117059 Rat Entrez Gene: 钙结合蛋白抗体393684 Zebrafish Omim: 114051 Human SwissProt: P07090 Chicken SwissProt: P22676 Human SwissProt: Q08331 Mouse SwissProt: P47728 Rat Unigene: 106857 Human Unigene: 2755 Mouse Unigene: 10321 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 钙结合蛋白(Calretinin,CR)主要存在于神经组织中，近10%的腺癌可以表达此蛋白的局部染色阳性，而绝大多数的间皮瘤为阳性表达，因此它是诊断间皮瘤的一个有用的标记物 。 钙结合蛋白是平滑肌和非肌性调控蛋白。它可以与肌动蛋白、肌球蛋白、原肌球蛋白和钙调素相互作用。
钙结合蛋白抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit