凝血酶原酶/纤维蛋白原2抗体
规格：1尘驳/1尘濒
英文名： FGL2
别名： Fibroleukin; Cytotoxic T-lymphocyte-specific protein; Fibrinogen-like protein 2; Fibrinogen like protein 2; Prothrombinase; Fibroleukin; pT49; T49; FGL2_HUMAN.
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Rat FGL2
交叉反应：搁补迟,
凝血酶原酶/纤维蛋白原2抗体细胞定位：分泌型蛋白
产物介绍：background: FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via凝血酶原酶/纤维蛋白原2抗体 a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1. Function: May play a role in physiologic lymphocyte functions at mucosal sites Subunit: Homotetramer; disulfide-linked. Subcellular Location: Secreted. Tissue Specificity: Constitutively expressed in cytotoxic T-cells. Similarity: Contains 1 fibrinogen C-terminal domain. Gene ID: 84586 Database 凝血酶原酶/纤维蛋白原2抗体links: Entrez Gene: 511711 Cow Entrez Gene: 10875 Human Entrez Gene: 14190 Mouse Entrez Gene: 84586 Rat Omim: 605351 Human SwissProt: Q14314 Human SwissProt: P12804 Mouse Unigene: 520989 Human Unigene: 292100 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. fgL-2蛋白是新近发现的一种凝血因子，它通过直接激活凝血酶原启动凝血过程。一 系列实验证明，该蛋白在肝细胞坏死中起到重要作用。对乙肝患者肝组织**组织化学染色hfg12在重型乙型肝炎患者高表达。 凝血酶原酶(简称fgl2)蛋白属于纤维蛋白原家族的一员,由活化的巨噬细胞表达,具有凝血酶原酶的活力,能催化凝血酶原转化为凝血酶,启动凝血过程.
凝血酶原酶/纤维蛋白原2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 t-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid