即刻早期基因础搁颁抗体
规格:1尘驳/1尘濒
英文名: ARC
别名: ARG3.1; Arc; Arg 3.1; Activity regulated cytoskeletal associated protein; Activity regulated cytoskeletal protein; Activity-regulated cytoskeleton-associated protein; Activity regulated cytoskeletal-a
分子量: 45kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ARC
交叉反应:Human, Mouse, Rat, Cow, Horse, Rabbit,
即刻早期基因础搁颁抗体细胞定位:细胞浆 细胞膜
产物介绍:background: Activity-regulated cytoskeleton-associated protein (ARC)in the brain and learning and memory, researchers believe: ARC protein is by strengthening the function of synaptic links in order to save the memory, including learning and memory and emotion. At present, the scientists will also Activity-regulated cytoskeleton-associated protein used to take drugs addiction. Function: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity.即刻早期基因础搁颁抗体 Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. Subunit: Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2. Subcellular Location: Cytoplasm, cytoskeleton. Endosome. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse. Similarity: Belongs 即刻早期基因础搁颁抗体to the ARC/ARG3.1 family. Gene ID: 23237 Database links: Entrez Gene: 23237 Human Entrez Gene: 11838 Mouse Entrez Gene: 54323 Rat Omim: 605235 Human SwissProt: Q7LC44 Human SwissProt: Q9WV31 Mouse SwissProt: Q63053 Rat Unigene: 40888 Human Unigene: 741621 Human Unigene: 25405 Mouse Unigene: 10086 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 该蛋白与大脑的学习记忆有关,研究人员认为:是ARC蛋白通过加强了突触的联系功能从而储存了这些记忆,包括情感和学习记忆。 目前,科学家也将该蛋白用于吸食毒品成瘾性的研究。
即刻早期基因础搁颁抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 细胞类型标志物 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid