酪氨酸蛋白激酶受体础10抗体
规格:1尘驳/1尘濒
英文名: EPHA10
别名: EPH receptor A10; EPHA 10; Epha10; EphA10s protein; EPHAA_HUMAN; Ephrin type A receptor 10; Ephrin type-A receptor 10.
分子量: 107kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human EPHA10
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
细胞定位:细胞膜 分泌型蛋白
酪氨酸蛋白激酶受体础10抗体产物介绍:background: The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date (1–3). While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development (1–3). The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph酪氨酸蛋白激酶受体础10抗体 receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, ephrin-A2 (ELF-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk) (4–7). Function: Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5. Subcellular Location: Isoform 1, 3: Cell membrane; Single-pass type I membrane protein (Probable). Isoform 2: Secreted (Probable). Tissue Specificity: Mainly expressed in testis. Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. Contains 1 Eph LBD (Eph ligand-binding) domain. Contains 2 fibronectin type-III domains.酪氨酸蛋白激酶受体础10抗体 Contains 1 protein kinase domain. Contains 1 SAM (sterile alpha motif) domain. Gene ID: 284656 Database links: Entrez Gene: 284656 Human Entrez Gene: 230735 Mouse Entrez Gene: 298528 Rat Omim: 611123 Human SwissProt: Q5JZY3 Human SwissProt: Q8BYG9 Mouse Unigene: 129435 Human Unigene: 171490 Mouse Unigene: 484372 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
酪氨酸蛋白激酶受体础10抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid