肿瘤坏死因子颁/****β抗体
规格:1尘驳/1尘濒
英文名: Lymphotoxin Beta
别名: LT beta; LT-beta; LTB; lymphotoxin beta (TNF superfamily, member 3); lymphotoxin beta; lymphotoxin-beta; OTTHUMP00000038214; p33; TNF C; TNF-C; TNFC; TNFC_HUMAN; TNFSF3; tumor necrosis factor C (lymph
分子量: 25kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Lymphoto
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位:细胞膜
肿瘤坏死因子颁/****β抗体产物介绍:background: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms. Function: Cytokine that binds to LTBR/TNFRSF3. May play a specific role in 肿瘤坏死因子颁/****β抗体immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional. Subunit: Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Tissue Specificity: Spleen and thymus. Similarity: Belongs to the tumor necrosis factor family. Database links: Entrez Gene: 4050 Human Entrez Gene: 16994 Mouse Omim: 600978 Human 肿瘤坏死因子颁/****β抗体SwissProt: Q06643 Human SwissProt: P41155 Mouse Unigene: 376208 Human Unigene: 1715 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤坏死因子颁/****β抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 **学 信号转导 生长因子和** 细胞因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid