血管内皮生长因子叠167
规格：1尘驳/1尘濒
英文名： VEGFB167
别名： VEGFB 167; VEGFB-167; Vascular endothelial growth factor B; VEGF B; VEGFB; VEGF-B; VEGF related factor; VEGFL; Vrf; vascular endothelial growth factor B isoform VEGFB-167 precursor; VEGFB_HUMAN.
分子量： 22kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VEGFB167
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Guinea Pig,
细胞定位：细胞外基质 分泌型蛋白
血管内皮生长因子叠167产物介绍：background: The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described and include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs). The VEGF protein family is comprised of VEGF, VEGF-B, VEGF-C and VEGF-D, all of which may exhibit angiogenic function in vivo. VEGF-B, which exists as two alternatively 血管内皮生长因子叠167spliced isoforms known as VEGF-B167 and VEGF-B186, is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF. VEGF-C binds to and specifically activates Flt-4 and Flk-1. Function: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. Subcellular Location: Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. Tissue Specificity: Expressed in all tissues except liver血管内皮生长因子叠167. Highest levels found in heart, skeletal muscle and pancreas. Post-translational modifications: VEGF-B167 is O-glycosylated. Similarity: Belongs to the PDGF/VEGF growth factor family. Gene ID: 7423 Database links: Entrez Gene: 7423 Human Entrez Gene: 22340 Mouse Entrez Gene: 89811 Rat Omim: 601398 Human SwissProt: P49765 Human SwissProt: P49766 Mouse SwissProt: O35485 Rat Unigene: 78781 Human Unigene: 15607 Mouse Unigene: 198550 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血管内皮生长因子叠167产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 生长因子和** 激酶和磷酸酶 细胞膜受体 血管内皮细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid