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内质网蛋白44抗体

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产物名称: 内质网蛋白44抗体
产物型号:
产物展商: 单克隆抗体/多克隆抗体
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简单介绍

内质网蛋白44抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。内质网蛋白44抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


内质网蛋白44抗体  的详细介绍

内质网蛋白44抗体

规格:1尘驳/1尘濒

英文名: TXNDC4

别名: Endoplasmic reticulum resident protein 44; Endoplasmic reticulum resident protein 44 kDa; Endoplasmic reticulum resident protein ERp44; ER protein 44; ERP44; KIAA0573; PDIA10; Protein disulfide isomer

分子量: 44kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human TXNDC4

交叉反应:Human, Mouse, Rat, Chicken, Cow, Horse,

细胞定位:细胞浆

内质网蛋白44抗体产物介绍:background: Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum. Function: Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved 内质网蛋白44抗体CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum. Subunit: Forms mixed disulfides with both ERO1L and ERO1LB and cargo folding intermediates. Directly interacts with ITPR1 in a pH-, redox state- and calcium-dependent manner, but not with ITPR2 or ITPR3. The strength of this interaction inversely correlates with calcium concentration. Subcellular Location: Endoplasmic reticulum lumen. Similarity: Contains 内质网蛋白44抗体 thioredoxin domain. Gene ID: 23071 Database links: Entrez Gene: 23071 Human Entrez Gene: 506157 Cow Entrez Gene: 474781 Dog Entrez Gene: 100414815 Marmoset (common) Entrez Gene: 76299 Mouse Entrez Gene: 100192437 Pig Entrez Gene: 298066 Rat Omim: 609170 Human SwissProt: Q3T0L2 Cow SwissProt: Q9BS26 Human SwissProt: Q9D1Q6 Mouse Unigene: 154023 Human Unigene: 317701 Mouse Unigene: 2459 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

内质网蛋白44抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  **学  染色质和核信号  转录调节因子  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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