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髓系、**、混合系白血病易位基因10抗体

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产物名称: 髓系、**、混合系白血病易位基因10抗体
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产物展商: 单克隆抗体/多克隆抗体
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简单介绍

髓系、**、混合系白血病易位基因10抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。髓系、**、混合系白血病易位基因10抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


髓系、**、混合系白血病易位基因10抗体  的详细介绍

髓系、**、混合系白血病易位基因10抗体

规格:1尘驳/1尘濒

英文名: AF10

别名: AF 10; AF10; AF10_HUMAN; ALL 1 fused gene from chromosome 10; ALL1 fused gene from chromosome 10; ALL1-fused gene from chromosome 10 protein; MLLT 10; MLLT10; Myeloid/lymphoid or mixed lineage leukemi

分子量: 109kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human AF10

交叉反应:Human, Mouse, Rat, Pig, Cow, Sheep,

细胞定位:细胞核

髓系、**、混合系白血病易位基因10抗体产物介绍:Function: Probably involved in transcriptional regulation. In vitro or as fusion protein with MLL has transactivation activity. Binds to cruciform DNA. Subunit: Self-associates. Interacts with FSTL3 isoform 2; the interaction enhances MLLT10 in vitro transcriptional activity and self-association. Interacts with YEATS4. Interacts with SS18. Interacts with DOT1L. Subcellular Location: Nucleus. Tissue Specificity: Expressed abundantly in testis. Post-translational modifications: Phosphorylated upon 髓系、**、混合系白血病易位基因10抗体DNA damage, probably by ATM or ATR. DISEASE: Note=A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein. Note=A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM. 髓系、**、混合系白血病易位基因10抗体Similarity: Contains 2 PHD-type zinc fingers. Gene ID: 8028 Database links: Entrez Gene: 8028 Human Entrez Gene: 17354 Mouse Omim: 602409 Human SwissProt: P55197 Human SwissProt: O54826 Mouse Unigene: 30385 Human Unigene: 209175 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

髓系、**、混合系白血病易位基因10抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:肿瘤  转录调节因子  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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