β3肾上腺素能受体抗体
规格：1尘驳/1尘濒
英文名： beta 3 Adrenergic Receptor
别名： beta3-adrenergic receptor; beta3-AR; adrenergic; beta-3- receptor; ADR B3; ADRB 3; ADRB3; ADRB3R; Adrenergic beta 3 receptor; B3AR; Beta 3 adrenoceptor; Beta 3 adrenoreceptor; Beta 3AR; B3AR; BETA3AR;
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ADRB3
交叉反应：Human, Mouse, Rat, Dog, Pig, Sheep,
细胞定位：细胞膜
β3肾上腺素能受体抗体产物介绍：background: beta 3 Adrenergic Receptor is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Beta adrenergic receptors are involved in the epenephrine and norepinephrine-induced activation of adenylate cyclase through the action of G proteins. beta 3 Adrenergic Receptor expression has been documented in adipose tissues, heart, and in smooth muscle of digestive and urinary tract organs (bladder, colon, small intestine, stomach, ureter). Utilization β3肾上腺素能受体抗体of alternate promoters and/or 3-prime untranslated regions may result in tissue-specific regulation of the expression of this protein. Function: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificityβ3肾上腺素能受体抗体: Expressed mainly in adipose tissues. Similarity: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily. Gene ID: 155 Database links: Entrez Gene: 155 Human Entrez Gene: 11556 Mouse Entrez Gene: 25645 Rat SwissProt: P13945 Human SwissProt: P25962 Mouse SwissProt: P26255 Rat Unigene: 2549 Human Unigene: 278475 Mouse Unigene: 10100 Rat Omim: 109691 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ARβ3是新近发现的,继β1和β2之后的第3个β型肾上腺素受体亚型.分子量：44KDa(404AA) 近年来研究表明:β3-肾上腺素受体该受体基因突变或基因多态性与机体肥胖及心血管**相关;心力衰竭时该受体的含量明显增加,β3肾上腺素能受体与心血管**的相关研究可能为心血管**的预测、防治的新方法.
β3肾上腺素能受体抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 神经生物学 生长因子和** 细胞膜受体 ***病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid