氨基丁酸转运蛋白痴骋础罢抗体
规格：1尘驳/1尘濒
英文名： SLC32A 1
别名： VGAT; bA122O1.1; GABA and glycine transporter; hVIAAT; SLC32A 1; solute carrier family 32 (GABA vesicular transporter) member 1; Solute carrier family 32 member 1; Vesicular GABA Amino Acid Transporte
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC32A 1
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
氨基丁酸转运蛋白痴骋础罢抗体产物介绍：background: Synaptic transmission involves the controlled exocytosis of vesicles containing specific neurotransmitters. Usually, neurotransmitters are synthesized in the cytoplasm of the cell and must be transported into synaptic vesicles for release. The vesicular GABA transporter (VGAT) is responsible for loading gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, from neuronal cytoplasm into synaptic vesicles and is expressed only in the nerve endings of inhibitory neurons that contain 氨基丁酸转运蛋白痴骋础罢抗体GABA and/or glycine. During neocortical development, VGAT expression barely precedes the maturation of inhibitory synaptogenesis, suggesting that it may contribute to the development of neocortical GABAergic circuitry. VGAT may also play a role in epileptogenesis and the recovery mechanisms that occur after a spontaneous seizure Function: Involved in the uptake of GABA and glycine 氨基丁酸转运蛋白痴骋础罢抗体into the synaptic vesicles. Subcellular Location: Cytoplasmic vesicle membrane; Multi-pass membrane protein. Tissue Specificity: Retina. Expressed throughout the horizontal cells or more specifically at the terminals. Similarity: Belongs to the amino acid/polyamine transporter 2 family. Gene ID: 140679 Database links: Entrez Gene: 140679 Human Entrez Gene: 22348 Mouse Entrez Gene: 83612 Rat SwissProt: Q9H598 Human SwissProt: O35633 Mouse SwissProt: O35458 Rat Unigene: 179080 Human Unigene: 143404 Mouse Unigene: 413854 Mouse Unigene: 10846 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
氨基丁酸转运蛋白痴骋础罢抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid