嗜中性粒细胞抗原颁顿177抗体
规格：1尘驳/1尘濒
英文名： CD177
别名： NB1 GP; PRV-1; PRV1; HNA-2a; NB1 glycoprotein; Neutrophil Glycoprotein NB1; RGD1562941; CD177 antigen; Polycythemia rubra vera protein 1; Human neutrophil alloantigen 2a; HNA-2a; CD177; NB1; CD177_HUM
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD177
交叉反应：Human, Dog, Cow, Horse, Guinea Pig,
细胞定位：细胞膜
嗜中性粒细胞抗原颁顿177抗体产物介绍：background: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be嗜中性粒细胞抗原颁顿177抗体 involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014] Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor.嗜中性粒细胞抗原颁顿177抗体 Tissue Specificity: Highly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET). Similarity: Contains 2 UPAR/Ly6 domains. Gene ID: 57126 Database links: Entrez Gene: 57126 Human Omim: 162860 Human SwissProt: Q8N6Q3 Human Unigene: 232165 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
嗜中性粒细胞抗原颁顿177抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 细胞表面分子 糖蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid