肿瘤相关表面抗原贰叠础骋9抗体
规格:1尘驳/1尘濒
英文名: RCAS1/EBAG9
别名: BAG9; Cancer associated surface antigen; Cancer associated surface antigen RCAS1; EB9; EBAG 9; Estrogen receptor binding fragment associated gene 9 protein; Estrogen receptor binding site associated a
分子量: 24kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RCAS1
交叉反应:Human, Mouse, Chicken, Pig, Cow, Rabbit,
细胞定位:细胞浆 细胞膜
肿瘤相关表面抗原贰叠础骋9抗体产物介绍:background: This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013] Function:肿瘤相关表面抗原贰叠础骋9抗体 May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases Subunit: Homodimer. Subcellular Location: Golgi apparatus membrane; Single-pass type III membrane protein. Note=According to PubMed:10426319, it also exists as a soluble form which has the same biological activities. The existence of such soluble form is however uncertain. Tissue Specificity: Widely expressed. Expressed in ovary, testis, prostate, thymus, muscle and heart, but not in 肿瘤相关表面抗原贰叠础骋9抗体small intestine, colon, lymph nodes, or peripherical blood lymphocytes. The protein is not detected in any of the above organs. Gene ID: 9166 Database links: Entrez Gene: 9166 Human Entrez Gene: 55960 Mouse Entrez Gene: 299864 Rat Omim: 605772 Human SwissProt: O00559 Human SwissProt: Q9D0V7 Mouse SwissProt: Q5PQP2 Rat Unigene: 409368 Human Unigene: 489725 Mouse Unigene: 64132 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤相关表面抗原贰叠础骋9抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 生长因子和** 细胞类型标志物 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid