感觉神经蛋白1抗体
规格:1尘驳/1尘濒
英文名: FAM84A
别名: FAM 84A; Family with sequence similarity 84 member A; family with sequence similarity 84, member A; FLJ35392; Neurologic sensory protein 1; Neurological/sensory 1; NSE 1; NSE1; PP11517; Protein FAM84A
分子量: 32kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NSE1/FAM
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Zebrafish,
细胞定位:
感觉神经蛋白1抗体产物介绍:background: FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44% amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 感觉神经蛋白1抗体can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells. Post-translational modifications: Isoform 2 is phosphorylated. Similarity:感觉神经蛋白1抗体 Belongs to the FAM84 family. Database links: Entrez Gene: 151354 Human Entrez Gene: 105005 Mouse Entrez Gene: 313969 Rat Omim: 611234 Human SwissProt: Q96KN4 Human SwissProt: Q9D650 Mouse SwissProt: B2RYB4 Rat Unigene: 260855 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
感觉神经蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid