单核细胞趋化蛋白1抗体
规格：1尘驳/1尘濒
英文名： MCP1
别名： MCP-1; monocyte chemotactic protein 1; CCL 2; CCL2; Chemokine C C motif ligand 2; Chemokine CC Motif Ligand 2; GDCF 2; GDCF 2 HC11; GDCF2; HC11; HSMCR30; JE; MCAF; MCP 1; MGC9434; Monocyte chemoattrac
分子量： 11kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from rat MCP-1
交叉反应：Mouse, Rat,
细胞定位：分泌型蛋白
单核细胞趋化蛋白1抗体产物介绍：background: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function 单核细胞趋化蛋白1抗体toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside. Function: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Subunit: Monomer or homodimer; in equilibrium. Binds to CCR2 and 单核细胞趋化蛋白1抗体CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Subcellular Location: Secreted. Post-translational modifications: Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Similarity: Belongs to the intercrine beta (chemokine CC) family. Gene ID: 24770 Database links: Entrez Gene: 6347 Human Entrez Gene: 20296 Mouse Entrez Gene: 24770 Rat Omim: 158105 Human SwissProt: P13500 Human SwissProt: P10148 Mouse SwissProt: P14844 Rat Unigene: 303649 Human Unigene: 290320 Mouse Unigene: 4772 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 生长因子和**（ Growth Factor and Hormones） 巨噬细胞趋化蛋白1(MCP1)具有多向性调节作用的核转录因子，它可诱导与**和炎症有关的多种基因转录.MCP-1**组化阳性信号主要位于胞浆内。
产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.单核细胞趋化蛋白1抗体
研究领域：肿瘤 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid