突触后蛋白颁搁滨笔罢抗体
规格：1尘驳/1尘濒
英文名： CRIPT
别名： CRIPT; CRIPT_HUMAN; Cysteine rich interactor of PDZ3; Cysteine rich PDZ binding protein; Cysteine-rich interactor of PDZ three; Cysteine-rich interactor of PDZ3; Cysteine-rich PDZ-binding protein; HSP
分子量： 11kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CRIPT
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow,
细胞定位：细胞浆 细胞膜
突触后蛋白颁搁滨笔罢抗体产物介绍：background: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. These proteins are physically and functionally linked to cytoskeletal and/or signaling proteins. CRIPT (for cysteine-rich interactor of PDZ three), a novel postsynaptic protein, binds specifically to the PDZ3 domain of PSD-95/SAP 90. CRIPT induces the recruitment of PSD-95/SAP 90 to microtubules, and it has been shown to bind directly to microtubules, indicating that it may be responsible for cytoskeletal anchoring of PSD-95/SAP 90. CRIPT is widely expressed outside of the brain and is highly突触后蛋白颁搁滨笔罢抗体 conserved from animals to plants suggesting a wider role in regulating cytoskeleton-membrane associations. Function: Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. Subunit: Interacts with TUBB1. Interacts strongly with the PDZ3 domain of members of the DLG4 family. Associates with microtubules (By similarity). Interacts with DLG4. Subcellular Location: Cytoplasm. Cell junction; 突触后蛋白颁搁滨笔罢抗体synapse. Cell projection; dendritic spine. Colocalizes with DLG4 in asymmetric synapses. Similarity: Belongs to the CRIPT family. Database links: UniProtKB/Swiss-Prot: Q9P021.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触后蛋白颁搁滨笔罢抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 细胞粘附分子 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid