突触融合结合蛋白6抗体
规格：1尘驳/1尘濒
英文名： Amisyn
别名： Amisyn; HSPC156; STXB6_HUMAN; STXBP6; Syntaxin binding protein 6; Syntaxin-binding protein 6.
分子量： 24kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Amisyn
交叉反应：Human, Mouse, Rat, Chicken, Cow, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
突触融合结合蛋白6抗体产物介绍：background: Amisyn is a mostly cytosolic protein related to Tomosyn which plays an important role in SNARE complex assembly. Amisyn contains a v-SNARE coiled coil homology domain that binds to Syntaxin 1A and weakly to Syntaxin 4. Three isoforms exist for Amisyn. Isoform 1 is the full length protein, isoform 2 has a different amino acid sequence between residues 204-210 and isoform 3 is missing amino acids 1-102 and contains a different sequence for amino acids 103-150. Amisyn lacks a transmembrane突触融合结合蛋白6抗体 domain and therefore is unable to assemble into a functional, membrane-anchored SNARE complex. This suggests that Amisyn may instead be acting to maintain SNARE conformation and facilitate the binding of VAMP-2. Amisyn can inhibit exocytosis independent of Syntaxin binding. Function: Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis. Subunit: Part of a ternary complex containing SNAP25 and STX1A that can be dissociated by NAPA and NSF突触融合结合蛋白6抗体. Interacts with STX4A. Subcellular Location: Cytoplasm. Membrane. Tissue Specificity: Detected at low levels in brain, and at very low levels in heart, adrenal gland, testis, liver and kidney. Similarity: Contains 1 v-SNARE coiled-coil homology domain. Database links: UniProtKB/Swiss-Prot: Q8NFX7.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触融合结合蛋白6抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 细胞粘附分子 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid