卵黄状黄斑病蛋白3抗体
规格：1尘驳/1尘濒
英文名： Bestrophin 3
别名： Vitelliform macular dystrophy 2 like protein 3; BEST 3; BEST3; BEST3_HUMAN; Bestrophin-3; Bestrophin3; Vitelliform macular dystrophy 2 like 3; Vitelliform macular dystrophy 2-like protein 3; VMD2L3.
分子量： 76kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Bestroph
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位：细胞膜
卵黄状黄斑病蛋白3抗体产物介绍：background: Bestrophin-3 is a 668 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (arg-phe-pro) motif and they function as anion channels. Expressed predominantly in skeletal muscle but also found in spinal 卵黄状黄斑病蛋白3抗体cord, brain, testis, thymus, retina and bone marrow, Bestrophin-3 forms calcium-sensitive chloride channels. In addition, Bestrophin-3 contains an AI (auto-inhibitory) domain that is capable of regulating the anion channel activity. Due to alternative splicing events, three isoforms exist for Bestrophin-3. Function: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Subcellular Location: Cell membrane卵黄状黄斑病蛋白3抗体. Tissue Specificity: Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina. Similarity: Belongs to the bestrophin family. Database links: UniProtKB/Swiss-Prot: Q8N1M1.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卵黄状黄斑病蛋白3抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid