卵黄状黄斑病蛋白4抗体
规格：1尘驳/1尘濒
英文名： Bestrophin 4
别名： BEST 4; BEST4; BEST-4; Bestrophin 4; Bestrophin4; Bestrophin-4; Vitelliform macular dystrophy 2 like 2; Vitelliform macular dystrophy 2 like protein 2; VMD2L2; BEST4_HUMAN.
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Bestroph
交叉反应：Human, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
卵黄状黄斑病蛋白4抗体产物介绍：background: Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the 卵黄状黄斑病蛋白4抗体cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina. Function: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Predominantly found in colon and the weakly in fetal brain, spinal cord, retina, lung, trachea, testis and placenta.卵黄状黄斑病蛋白4抗体 Similarity: Belongs to the bestrophin family. Gene ID: 266675 Database links: Entrez Gene: 510542 Cow Entrez Gene: 482521 Dog Entrez Gene: 100052813 Horse Entrez Gene: 266675 Human Entrez Gene: 100345949 Rabbit Entrez Gene: 689103 Rat Omim: 607336 Human SwissProt: Q8NFU0 Human Unigene: 302513 Human Unigene: 84672 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卵黄状黄斑病蛋白4抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid