粘附分子滨驳骋样结构域蛋白1抗体
规格：1尘驳/1尘濒
英文名： AMIGO1
别名： Adhesion molecule with Ig like domain 1; ali2; Alivin 2; AMIGO 1; AMIGO; AMIGO protein; Amphoterin induced gene and ORF (Amigo); Amphoterin induced gene and ORF; Amphoterin induced protein 1; KIAA1163
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AMIGO1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
粘附分子滨驳骋样结构域蛋白1抗体产物介绍：background: The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or 粘附分子滨驳骋样结构域蛋白1抗体heterophilic cell-cell interaction and signal transduction. Function: AMIGO1 promotes growth and fasciculation of neurites from cultured hippocampal neurons. It may be involved in fasciculation as well as myelination of developing neural axons and have a role in regeneration as well as neural plasticity in the nervous system. AMIGO1 may also mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Subunit: Homodimer, and heterodimer with AMIGO2 and AMIGO3.粘附分子滨驳骋样结构域蛋白1抗体 Subcellular Location: Membrane; Single-pass type I membrane protein. Cell projection; axon. Note: Associated with axons of neuronal cells. Similarity: Belongs to the immunoglobulin superfamily. AMIGO family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 6 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Database links: UniProtKB/Swiss-Prot: Q86WK6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
粘附分子滨驳骋样结构域蛋白1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid