钙粘附蛋白8抗体
规格：1尘驳/1尘濒
英文名： Cadherin 8
别名： CADH8_HUMAN; Cadherin 8, type 2; Cadherin-8; CDH 8; CDH8; Putative protein product of Nbla04261.
分子量： 81kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Cadherin
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
钙粘附蛋白8抗体产物介绍：background: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity.钙粘附蛋白8抗体 Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008]. Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Subcellular Location: Cell membrane. Tissue Specificity: Mainly expressed in 钙粘附蛋白8抗体brain. Found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts. Similarity: Contains 5 cadherin domains. Database links: UniProtKB/Swiss-Prot: P55286.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙粘附蛋白8抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid