连接蛋白闯笔贬4抗体
规格：1尘驳/1尘濒
英文名： Junctophilin 4
别名： JP-4; Jph4; JPH4_HUMAN; JPHL1; Junctophilin4; Junctophilin like 1 protein; Junctophilin-4; Junctophilin-like 1 protein; KIAA1831.
分子量： 66kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Junctoph
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞膜
连接蛋白闯笔贬4抗体产物介绍：background: This gene encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma membrane and the endoplasmic/sarcoplasmic reticulum in excitable cells. The encoded protein contains a conserved N-terminal repeat region called the membrane occupation and recognition nexus sequence that is found in other members of the junctophilin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] Function: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane 连接蛋白闯笔贬4抗体with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity). Subcellular Location: Cell membrane; Peripheral membrane protein (By similarity). Endoplasmic reticulum membrane; Single-pass type IV membrane protein (By similarity). Note=Localized predominantly on the plasma membrane. The transmembrane连接蛋白闯笔贬4抗体 domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane (By similarity). Similarity: Belongs to the junctophilin family. Contains 8 MORN repeats. Database links: Entrez Gene: 84502 Human Entrez Gene: 319984 Mouse Entrez Gene: 445271 Rat SwissProt: Q96JJ6 Human SwissProt: Q80WT0 Mouse SwissProt: Q69FB3 Rat Unigene: 597841 Human Unigene: 19047 Mouse Unigene: 163297 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
连接蛋白闯笔贬4抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学 神经生物学 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid