神经细胞粘附分子2抗体
规格：1尘驳/1尘濒
英文名： NCAM2
别名： N CAM 2; N CAM 21; N CAM2; N CAM21; N-CAM-2; NCAM 2; NCAM 21; NCAM-2; Ncam2; NCAM2_HUMAN; NCAM21; Neural cell adhesion molecule 2; OCAM GPI; R4B12; RB 8 neural cell adhesion molecule; RB8 neural cell
分子量： 91kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NCAM2
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞膜
神经细胞粘附分子2抗体产物介绍：background: NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2. NCAM2 contains five immunoglobulin-like domains, two Fibronectin type III domains, a transmembrane domain and a cytoplasmic domain. The gene is expressed most strongly in human and fetal brain. NCAM2 is a member of the neural cell adhesion molecule (NCAM) family. NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role神经细胞粘附分子2抗体 in embryogenesis and development. NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells. Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line; this binding is induced by cytokines that activate Stat5. Neither Stat1 nor Stat3 bind to this region, despite sharing a consensus binding sequence with Stat5. Function: May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons. Subunit: Contains 2 fibronectin type-III domains. Contains 5 Ig-like C2-type (immunoglobulin-like) domains神经细胞粘附分子2抗体. Subcellular Location: Cell membrane. Tissue Specificity: Expressed most strongly in and fetal brain. Similarity: Contains 2 fibronectin type-III domains. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. Database links: UniProtKB/Swiss-Prot: O15394.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经细胞粘附分子2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 细胞粘附分子 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid