神经生长调节蛋白1抗体
规格:1尘驳/1尘濒
英文名: NEGR1
别名: A kindred of IgLON; DMML2433; IgLON family member 4; IGLON4; KILON; Neuronal growth regulator 1; Neurotractin; Ntra; PRO4993; UNQ2433; NEGR1_HUMAN.
分子量: 31kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NEGR1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
神经生长调节蛋白1抗体产物介绍:background: NEGR1 is a 354 amino acid protein belonging to the IgLON family and immunoglobulin superfamily. NEGR1 may play a role in cell adhesion and regenerative axon sprouting in the mammalian brain and is highly expressed in hippocampus, cerebrum and brainstem, with much lower levels found in cerebellum. Localizing to the cell membrane at the glycosylphosphatidylinositol anchor (GPI) anchor, NEGR1 contains three Ig-like C2-type (immunoglobulin-like) domains. NEGR1 is encoded by a gene that maps to神经生长调节蛋白1抗体 human chromosome 1p31.1, and is one of several loci associated with body mass index (BMI), possibly contributing to the development of obesity. Function: NEGR1 may be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor Similarity: Belongs to the神经生长调节蛋白1抗体 immunoglobulin superfamily. IgLON family. Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Database links: UniProtKB/Swiss-Prot: Q7Z3B1.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经生长调节蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:发育生物学 神经生物学 细胞粘附分子 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid