神经元齿连锁蛋白/儿童自闭症相关蛋白抗体
规格：1尘驳/1尘濒
英文名： NLGN4X
别名： X-linked; HNLX; KIAA1260; Neuroligin X; Neuroligin-4; NLGN4; NLGN 4; NLGN4X; Neuroligin 4 X linked; Neuroligin 4; Neuroligin X; NLGN; NLGN-4; NLGN4X; NLGN4Y; NLGNX_HUMAN.
分子量： 92kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NLGN4X
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Zebrafish, Chimpanzee,
细胞定位：细胞膜
神经元齿连锁蛋白/儿童自闭症相关蛋白抗体产物介绍：background: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]. Function: Putative neuronal cell surface protein involved in cell-cell-interactions. Subunit: Belongs to the type-B carboxylesterase/lipase family. Subcellular Location: Membrane. Tissue Specificity: Expressed at highest levels in heart. Expressed at lower levels in liver, skeletal神经元齿连锁蛋白/儿童自闭症相关蛋白抗体 muscle and pancreas and at very low levels in brain. DISEASE: Defects in NLGN4X may be the cause of susceptibility to autism X-linked type 2 (AUTSX2). AUTSX2 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Defects in NLGN4X may be the cause of susceptibility to X-linked Asperger syndrome 神经元齿连锁蛋白/儿童自闭症相关蛋白抗体2 (ASPGX2). ASPGX2 is considered to be a form of childhood autism. Similarity: Belongs to the type-B carboxylesterase/lipase family. Gene ID: 57502 Database links: Entrez Gene: 57502 Human Omim: 300427 Human SwissProt: Q8N0W4 Human Unigene: 21107 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经元齿连锁蛋白/儿童自闭症相关蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学 神经生物学 细胞粘附分子 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid