轴突生长诱向因子骋2/神经突起生长导向因子骋2抗体
规格：1尘驳/1尘濒
英文名： Netrin G2
别名： Laminet 2; Laminet-2; Laminet2;Lmnt2; Lmnt 2; Lmnt-2; Netrin-G2; NetrinG2; NTNG1; NTNG 1; NTNG-1; NTNG2; NTNG 2; NTNG-2; NTNG2_HUMAN; bA479K20.1; LHLL9381.
分子量： 56kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Netrin G
交叉反应：Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位：细胞膜
轴突生长诱向因子骋2/神经突起生长导向因子骋2抗体产物介绍：background: Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin-1, which is the mammalian homolog of UNC-6 from C. elegans, is largely expressed in the developing nervous system and in mesodermal tissues. Netrin-1 is expressed by the floor plate as either a cell associated protein or in a diffusible form, and it binds to several surface receptor components, including deleted in轴突生长诱向因子骋2/神经突起生长导向因子骋2抗体 colorectal cancer (DCC) and neogenin. During embryonic development, netrin-1 diffuses through the neuronal epithelium, where it forms a chemoattractant gradient that directs axonal migration to the ventral midline of the spinal cord. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins, as the cells are repelled, rather than attracted, by the netrin gradient. Function: Promotes neurite outgrowth of both axons and dendrites. Subunit: Interacts with LRRC4 (By similarity).轴突生长诱向因子骋2/神经突起生长导向因子骋2抗体 Subcellular Location: Cell membrane. Post-translational modifications: N-glycosylated (By similarity). Similarity: Contains 3 laminin EGF-like domains. Contains 1 laminin N-terminal domain. Gene ID: 84628 Database links: Entrez Gene: 84628 Human Entrez Gene: 171171 Mouse Entrez Gene: 311836 Rat SwissProt: Q96CW9 Human SwissProt: Q8R4F1 Mouse Unigene: 163642 Human Unigene: 442448 Mouse Unigene: 218540 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
轴突生长诱向因子骋2/神经突起生长导向因子骋2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 生长因子和** 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid