轴突蛋白2抗体
规格：1尘驳/1尘濒
英文名： Neurexin II alpha
别名： Neurexin 2; Neurexin-2; Neurexin2; Neurexin II; Neurexin II alpha; NRXN 2; NRXN-2; NRXN2; NRX2A_HUMAN.
分子量： 182kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Neurexin
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞膜
轴突蛋白2抗体产物介绍：background: This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G 轴突蛋白2抗体domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).[provided by RefSeq, Jun 2010] Function: Neurexin 2 alpha belongs to the Neurexin family, a group of neuronal proteins that function as cell adhesion molecules during synaptogenesis and intracellular signaling. Mammalian genomes contain just three neurexin genes. However, many neurexin isoforms may be expressed through the use of two alternative promoters and alternative splicing at up to five different positions. Subunit: The laminin G-like domain 1 binds to NXPH1. Specific isoforms bind to alpha-dystroglycan. Interacts with INADL. Subcellular Location: Membrane; single-pass type I membrane protein. Tissue Specificity: Predominantly expressed in brain. Similarity: Belongs to the neurexin family. Contains 轴突蛋白2抗体3 EGF-like domains. Contains 6 laminin G-like domains. Gene ID: 9379 Database links: Entrez Gene: 9379 Human Entrez Gene: 18190 Mouse Entrez Gene: 116595 Rat SwissProt: Q9P2S2 Human SwissProt: Q63374 Rat Unigene: 372938 Human Unigene: 329616 Mouse Unigene: 414022 Mouse Unigene: 11282 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
轴突蛋白2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 细胞粘附分子 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid