原钙粘附蛋白11齿抗体
规格：1尘驳/1尘濒
英文名： PCDH11X
别名： PCDH11; PCDH22; PCDHX; PCDHY; Protocadherin 11; Protocadherin 11 X linked; Protocadherin 11 Y linked; Protocadherin 22; Protocadherin on the X chromosome; Protocadherin on the Y chromosome; Protocadhe
分子量： 145kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PCDH11X
交叉反应：Human, Mouse, Rat, Pig, Horse, Rabbit, Sheep,
原钙粘附蛋白11齿抗体细胞定位：细胞膜
产物介绍：background: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to 原钙粘附蛋白11齿抗体coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with variable cytoplasmic domains. [provided by RefSeq, Jul 2008]. Function: Potential calcium-dependent cell-adhesion protein. Subcellular Location: Cell membrane; Single-pass type I membrane protein (Potential). Tissue Specificity: Expressed strongly in fetal brain原钙粘附蛋白11齿抗体 and brain (cortex, amygdala, thalamus, substantia nigra, hippocampus, caudate nucleus and corpus callosum). Expressed at low level in testis. Similarity: Contains 7 cadherin domains. Database links: Entrez Gene: 27328 Human Entrez Gene: 245578 Mouse Omim: 300246 Human SwissProt: Q9BZA7 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原钙粘附蛋白11齿抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 细胞粘附分子 细胞骨架 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid