原钙粘附蛋白α5抗体
规格:1尘驳/1尘濒
英文名: PCDHA5
别名: Cadherin related neuronal receptor 6; CNR 6; CNR6; CNRN 6; CNRN6; CNRS 6; CNRS6; CRNR 6; CRNR6; Ortholog of mouse CNR6; PCDH alpha5; PCDHA 5; Protocadherin alpha 5; PCDA5_HUMAN.
分子量: 99kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PCDHA5
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位:细胞膜
原钙粘附蛋白α5抗体产物介绍:background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHA5 (Protocadherin alpha-5) is one of fifteen members of the protocadherin alpha protein family that is expressed in neurons. PCDHA5 is a 936 amino acid single-pass type I membrane protein containing 6 cadherin 原钙粘附蛋白α5抗体domains. Localized to the cell membrane, PCDHA5 functions as a calcium-dependent cell-adhesion protein that is present in synaptic junctions and is essential to the establishment and maintenance of certain cell-cell interactions. PCDHA5 is expressed as 3 isoforms produced by alternative splicing. Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. Subcellular Location: Cell membrane; Single pass type I membrane protein. Similarity: Contains 6原钙粘附蛋白α5抗体cadherin domains. Database links: UniProtKB/Swiss-Prot: Q9Y5H7.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原钙粘附蛋白α5抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞外基质 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid