原钙粘附蛋白α8抗体
规格：1尘驳/1尘濒
英文名： PCDHA8
别名： KIAA0345 like 6; PCDH ALPHA8; Protocadherin alpha 8; PCDA8_HUMAN; PCDH alpha 8; PCDH-alpha-8; Protocadherin alpha 8; Protocadherin alpha-8.
分子量： 100kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PCDHA8
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞膜
原钙粘附蛋白α8抗体产物介绍：background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHA8 (protocadherin alpha 8) is a 950 amino acid single-pass type I membrane protein that contains six cadherin domains and is encoded by a gene which is located within the protocadherin alpha gene原钙粘附蛋白α8抗体 cluster on human chromosome 5. Existing as multiple alternatively spliced isoforms, PCDHA8 functions as a potential calcium-dependent cell adhesion protein that may be involved in the establishment and maintenance of neuronal connections within the brain. Function: PCDHA8 is most likely to play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has 原钙粘附蛋白α8抗体been observed and additional variants have been suggested but their full-length nature has yet to be determined. Two different isoforms are known. Subcellular Location: Cell membrane; Single-pass type I membrane protein Similarity: Contains 6 cadherin domains. Database links: UniProtKB/Swiss-Prot: Q9Y5H6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原钙粘附蛋白α8抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid