原钙粘蛋白15抗体
规格：1尘驳/1尘濒
英文名： PCDHB15
别名： PCDH beta15; PCDHB 15; PCDHB15; PCDHB-15; Protocadherin beta 15; PCDHB 22; PCDHB-22; PCDHB22; PCDBF_HUMAN.
分子量： 83kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PCDHB15.
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞膜
原钙粘蛋白15抗体产物介绍：background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. Pcdhb22 (protocadherin beta 22), also known as PcdhbV or Pcdhb15, is a 794 amino acid murine protein that is thought to function as a calcium-dependent cell-adhesion protein. Pcdhb22 is a homolog of human PCDHB15 (protocadherin beta 15), a 787 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB15) do not use 原钙粘蛋白15抗体constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Function: Protocadherin beta 15 (PCDHB15) is a member of the protocadherin family. Protocadherins constitute the largest subgroup within the cadherin family of calcium-dependent cell-cell adhesion molecules. They are neural cell surface proteins which are present at synaptic junctions. Their specific functions are unknown but they may be involved in the establishment and function of specific 原钙粘蛋白15抗体neuronal connections in the brain. PCDHB15 is one of sixteen tandemly arranged genes in the PCDHB gene cluster on chromosome 5q31. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Similarity: Contains 6 cadherin domains. Database links: Entrez Gene: 56121 Human Omim: 606341 Human SwissProt: Q9Y5E8 Human Unigene: 130757 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原钙粘蛋白15抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid