原钙粘蛋白β4抗体
规格:1尘驳/1尘濒
英文名: PCDHB4
别名: PCDB4_HUMAN; PCDH beta4; PCDH-beta-4; PCDHB4; PCDHB 4; PCDHB-4; Pcdhb5A; PcdhbD; Protocadherin beta-4.
分子量: 84kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PCDHB4
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
原钙粘蛋白β4抗体产物介绍:background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB4 (Protocadherin beta-4) is a 795 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced 原钙粘蛋白β4抗体to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB4) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB4 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal原钙粘蛋白β4抗体connections in the brain. Subunit: Contains 6 cadherin domains. Subcellular Location: Cell membrane. Similarity: Contains 6 cadherin domains. Database links: UniProtKB/Swiss-Prot: Q9Y5E5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原钙粘蛋白β4抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid