角质蛋白β抗体
规格：1尘驳/1尘濒
英文名： SPRR3
别名： 22 kDa pancornulin; Cornifin beta; Cornifin B; Esophagin; Small proline rich protein 3; Small proline-rich protein 3; SPRC; Sprr3; Esophagin; SPRR3_HUMAN.
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SPRR3/Co
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
角质蛋白β抗体产物介绍：background: Esophagin, also known as small proline-rich protein 3 (SPR3) or Cornifin ∫, belongs to the cornifin family of cornified-envelope structural proteins. It is expressed in mucosal epithelia such as esophagus and tongue and is strongly induced during epidermal keratinocyte differentiation. Due to its highly inducible nature, Esophagin is considered a marker of squamous differentiation. Esophagin serves as a cross-linking protein within the cornified cell envelope and may play a role in the maintenance of normal 角质蛋白β抗体esophageal epithelial homeostasis. It shares significant homology with the related proteins, SPRR1 and SPRR2. Esophagin is typically not expressed in healthy human epithelium, but its expression is upregulated in numerous hyperproliferative disorders of the skin. Contrastly, its expression is dramatically downregulated in esophageal squamous cell carcinoma. Function: Cross-linked envelope protein of keratinocytes. 角质蛋白β抗体Subunit: Belongs to the cornifin (SPRR) family. Subcellular Location: Cytoplasm. Similarity: Belongs to the cornifin (SPRR) family. Database links: Entrez Gene: 6707 Human Omim: 182271 Human SwissProt: Q9UBC9 Human Unigene: 139322 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
角质蛋白β抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid