脑特异性蛋白叠笔齿抗体
规格:1尘驳/1尘濒
英文名: NAP1L2
别名: Brain specific gene BPX; BPX; Brain specific protein, X linked; MGC26243; Nucleosome assembly protein 1 like 2; NP1L2_HUMAN.
分子量: 53kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NAP1L2
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位:细胞核
脑特异性蛋白叠笔齿抗体产物介绍:background: Proper nucleosome assembly is critical for compacting DNA into chromatin. In human and mouse there are 5 protein-coding genes which comprise the nucleosome assembly protein (NAP) family. NAP1L1 (NAP1) and NAP1L4 (NAP2) are ubiquitously expressed family members which have been the most extensively studied. The remaining three family members脑特异性蛋白叠笔齿抗体, NAP1L2, NAP1L3 and NAP1L5 are neuron-specific nucleosome assembly proteins translated from intronless genes which are monoallelically expressed. NAP1L2 (nucleosome assembly protein 1-like 2), also known as BPX (brain specific protein, X-linked), is a 460 amino acid protein containing acidic domains which are thought to mediate histone interactions. NAP1L2 binds to chromatin and interacts with 脑特异性蛋白叠笔齿抗体Histones H3 and H4. The function of NAP1L2 is not clearly defined although evidence suggests that NAP1L2 influences histone acetylation and therefore may play a significant role in regulating transcription in developing neurons. Function: NAP1L2 is a member of the nucleosome assembly protein (NAP) family. Subcellular Location: Nuclear Similarity: Belongs to the nucleosome assembly protein (NAP) family. Database links: UniProtKB/Swiss-Prot: Q9ULW6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑特异性蛋白叠笔齿抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:染色质和核信号 神经生物学 细胞粘附分子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid