跨膜丝氨酸蛋白酶5抗体
规格：1尘驳/1尘濒
英文名： TMPRSS5
别名： Spinesin; TMPRSS 5; TMPRSS-5; TMPRSS5; TMPS5_HUMAN; Transmembrane protease serine 5; Transmembrane protease, serine 5 (spinesin); Transmembrane protease, serine 5; MGC141886; MGC148044; OTTHUMP0000023
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TMPRSS5
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞膜
跨膜丝氨酸蛋白酶5抗体产物介绍：background: Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed 跨膜丝氨酸蛋白酶5抗体specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness. Function: May play a role in hearing. Subcellular Location: Cell membrane. Post-translational modifications: Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord. DISEASE: Note=Defects in 跨膜丝氨酸蛋白酶5抗体TMPRSS5 may be a cause of deafness. Similarity: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. Contains 1 SRCR domain. Gene ID: 80975 Database links: Entrez Gene: 80975 Human Entrez Gene: 80893 Mouse Entrez Gene: 266681 Rat Omim: 606751 Human SwissProt: Q9H3S3 Human SwissProt: Q9ER04 Mouse Unigene: 46720 Human Unigene: 72799 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
跨膜丝氨酸蛋白酶5抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 跨膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid