核转录因子厂翱齿22抗体
规格:1尘驳/1尘濒
英文名: SOX22
别名: SOX12; Homo sapiens SRY (sex determining region Y) box 12; Protein SOX-22; SOX 12; SOX 12 protein; SOX 22; SOX 22 protein; sox12; SOX12 protein; SOX12_HUMAN; SOX22 protein; SRY (sex determining region
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SOX22
交叉反应:Human, Mouse, Rat, Cow,
细胞定位:细胞核
核转录因子厂翱齿22抗体产物介绍:background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development 核转录因子厂翱齿22抗体and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Function: Binds to the sequence 5'-AACAAT-3' (By similarity). Subcellular Location: Nucleus. Tissue Specificity: Expressed most abundantly in the CNS. 核转录因子厂翱齿22抗体Also expressed in fetal brain and kidney and heart, pancreas, testis and ovary. Other tissues were only weakly positive. Similarity: Contains 1 HMG box DNA-binding domain. Database links: Entrez Gene: 6666 Human Entrez Gene: 20667 Mouse Omim: 601947 Human SwissProt: O15370 Human SwissProt: Q04890 Mouse Unigene: 43627 Human Unigene: 712815 Human Unigene: 28424 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核转录因子厂翱齿22抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid