驱动蛋白2抗体
规格：1尘驳/1尘濒
英文名： KLC1
别名： Kinesin 2 60/70kDa; Kinesin light chain 1; Kinesin2; Kinesin-2; KLC 1; KLC; KLC1; KLC1_HUMAN; KNS 2; KNS 2A; KNS2; KNS2A; Medulloblastoma antigen MU MB 2.50; MGC15245.
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KLC1
交叉反应：Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Zebrafish, Sheep,
细胞定位：细胞浆
驱动蛋白2抗体产物介绍：background: The kinesin family of motor proteins comprise at least two forms of conventional kinesin (kinesin-I). They are encoded by different genes and designated ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells. Conventional kinesin is a heterotetramer of two kinesin heavy chain subunits and two kinesin light chain subunits. While the kinesin heavy chain contains motor activity, evidence suggests that the kinesin light chain is involved in 驱动蛋白2抗体either modulation of kinesin heavy chain activity or in cargo binding. The motor protein kinesin is a heterotetramer composed of two heavy chains and two light chains. Kinesin motor activity is dependent on the presence of ATP and microtubules. Function: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. Subunit: Belongs to the kinesin light chain family. Contains 6 TPR repeats. Subcellular Location驱动蛋白2抗体: Cytoplasm; cytoskeleton. Tissue Specificity: Found in a variety of tissues. Mostly abundant in brain and spine. Post-translational modifications: Isoform I is phosphorylated on Ser-600. Isoform J is phosphorylated on Ser-631. Similarity: Belongs to the kinesin light chain family. Contains 6 TPR repeats. Gene ID: 3831 Database links: Entrez Gene: 3831 Human Entrez Gene: 16593 Mouse Entrez Gene: 171041 Rat Omim: 600025 Human SwissProt: Q07866 Human SwissProt: O88447 Mouse SwissProt: P37285 Rat Unigene: 20107 Human Unigene: 657678 Human Unigene: 278357 Mouse Unigene: 106230 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
驱动蛋白2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid