突触融合蛋白6抗体
规格：1尘驳/1尘濒
英文名： Syntaxin 6
别名： STX 6; STX6; STX-6; STX6_HUMAN; Syntaxin-6; Syntaxin6.
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Syntaxin
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
突触融合蛋白6抗体产物介绍：background: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. 突触融合蛋白6抗体The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6. Function: Involved in intracellular vesicle trafficking. Subunit: Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3 突触融合蛋白6抗体(By similarity). Interacts with GOPC. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A. Subcellular Location: Golgi apparatus membrane. Similarity: Belongs to the syntaxin family. Contains 1 t-SNARE coiled-coil homology domain. Database links: UniProtKB/Swiss-Prot: O43752.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触融合蛋白6抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid