大脑富含鸟苷酸激酶相关蛋白抗体
规格：1尘驳/1尘濒
英文名： BEGAIN
别名： BEGAIN; BEGIN; Brain enriched guanylate kinase associated protein; Brain-enriched guanylate kinase-associated homolog (rat); KIAA1446; SAP90/PSD95 Associated Proteins; SAPAP; BEGIN_HUMAN.
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BEGAIN
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：细胞浆 细胞膜
大脑富含鸟苷酸激酶相关蛋白抗体产物介绍：background: BEGAIN is a 593 amino acid protein that localizes to cytoplasm and membrane. BEGAIN interacts with PSD-95 and SAPAP1 and forms a ternary complex and may sustain the structure of the postsynaptic density (PSD). BEGAIN is a novel PSD component associated with the core complex of PSD-95 and SAPAP. Because BEGAIN and SAPAP interact with the same region of PSD-95, BEGAIN and SAPAP may compete for the binding to PSD-95 and cannot interact with PSD-95 simultaneously. The C-terminal region of BEGAIN is involved in the interaction with PSD-95 whereas the N-terminal region has a coiled-coil structure that may interact with大脑富含鸟苷酸激酶相关蛋白抗体 other molecules. BEGAIN is specifically expressed in brain and enriched in the PSD fraction. BEGAIN is also expressed in neurons and enriched at synaptic junctions, and is likely involved in the organization of synaptic junction components. Function: Brain-enriched guanylate kinase-associated protein (BEGAIN) interacts with postsynaptic density (PSD)-95/synapse-associated protein (SAP) 90. BEGAIN has been detected in nuclei and at synapses in neurons. Subunit: Interacts with DLG4 and DLGAP1 and forms a ternary complex (By similarity).大脑富含鸟苷酸激酶相关蛋白抗体 Subcellular Location: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity). Database links: Entrez Gene: 57596 Human Entrez Gene: 380785 Mouse Entrez Gene: 79146 Rat Entrez Gene: 443287 Sheep SwissProt: Q9BUH8 Human SwissProt: Q68EF6 Mouse SwissProt: O88881 Rat SwissProt: Q6R6L0-4 Sheep Unigene: 211751 Human Unigene: 342085 Mouse Unigene: 30036 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
大脑富含鸟苷酸激酶相关蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid