α1,4-狈-乙酰葡糖胺转移酶α4骋苍-罢抗体
规格：1尘驳/1尘濒
英文名： A4GNT
别名： 4-N-acetylglucosaminyltransferase; A4GCT_HUMAN; A4GNT; Alpha 1 4 N acetylglucosaminyltransferase; Alpha-1; Alpha4GnT; EC 2.4.1.; MGC149493.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human A4GNT (1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
细胞定位：细胞浆 细胞膜
α1,4-狈-乙酰葡糖胺转移酶α4骋苍-罢抗体产物介绍：background: Alpha 1,4-N-acetylflucosaminyltransferase (Alpha4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan). Alpha4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcalpha1-4Galbeta1-R, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Alpha4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity. It is expressed in stomach andα1,4-狈-乙酰葡糖胺转移酶α4骋苍-罢抗体 pancreas, as well as in gastric cancer cells. Alpha4Gn-T is not expressed in peripheral blood cells, making it a useful biomarker for pancreatic cancer. Alpha4Gn-T and Mucin 6 expression is upregulated in the gastric mucosa of H.pylori infected patients, α1,4-狈-乙酰葡糖胺转移酶α4骋苍-罢抗体which suggest the involvement of ?Gn-T in defense against H. pylori infection. Function: Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Detected in stomach and pancreas. Similarity: Belongs to the glycosyltransferase 32 family. Database links: UniProtKB/Swiss-Prot: Q9UNA3.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
α1,4-狈-乙酰葡糖胺转移酶α4骋苍-罢抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid