突触结合蛋白12抗体
规格：1尘驳/1尘濒
英文名： Synaptotagmin XII
别名： SRG1; Synaptotagmin 12; Synaptotagmin XII; Synaptotagmin-12; Syt12; SYT12_HUMAN; SytXII.
分子量： 47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Synaptot
交叉反应：Human, Mouse, Rat, Dog, Pig, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
突触结合蛋白12抗体产物介绍：background: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in突触结合蛋白12抗体 regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature. Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Subunit: Homodimer. Can also form heterodimers Subcellular Location: 突触结合蛋白12抗体Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Similarity: Belongs to the synaptotagmin family. Contains 2 C2 domains. Database links: UniProtKB/Swiss-Prot: Q8IV01.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触结合蛋白12抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid