生长抑素受体5抗体
规格：1尘驳/1尘濒
英文名： Somatostatin Receptor 5
别名： somatostatin receptor 5; SS5R; Somatostatin receptor subtype 5; Somatostatin receptor type 5; SS 5R; SS5 R; SST R5; SSTR 5; SSTR5; SS-5-R; SS5-R; SS5R; SSR5_HUMAN.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SSTR5
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
细胞定位：细胞膜
生长抑素受体5抗体产物介绍：background: Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, 生长抑素受体5抗体Feb 2010] Function: Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or kidney, liver, pancreas, uterus生长抑素受体5抗体, spleen, lung, thyroid or ovary. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 6755 Database links: Entrez Gene: 6755 Human Entrez Gene: 20609 Mouse Entrez Gene: 25354 Rat Omim: 182455 Human SwissProt: P35346 Human SwissProt: O08858 Mouse SwissProt: P30938 Rat Unigene: 449840 Human Unigene: 728117 Human Unigene: 353282 Mouse Unigene: 91342 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. SSTR5为G-蛋白偶联的细胞膜受体,SSTR5的表达与肿瘤的分布、发生和发展中起重要作用。
生长抑素受体5抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞膜受体 G蛋白偶联受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid