骋蛋白偶联受体135/松弛素受体3抗体
规格：1尘驳/1尘濒
英文名： Relaxin 3 receptor 1
别名： Relaxin Receptor 3; G protein coupled receptor GPCR135; G protein coupled receptor SALPR; G-protein coupled receptor SALPR; GPCR SALPR; GPCR 135; GPCR135; Gprotein coupled receptor SALPR; Relaxin 3 re
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Relaxin
交叉反应：Human, Mouse, Rat, Cow, Horse,
细胞定位：细胞膜
骋蛋白偶联受体135/松弛素受体3抗体产物介绍：background: Relaxin Receptor 3 is a G protein-coupled receptor that binds Relaxin 3 and influences differentiation and maintenance of the nervous system. Relaxin Receptor 3 shares sequence similarity with somatostatin receptors and angiotensin receptors. It mediates central processing of sensory signals in the rat and is thought to be a modulator of stress responses. Relaxin Receptor 3 is present in the brain, with highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, and low level expression in cerebellum. In peripheral tissues there are high levels in adrenal glands and low levels in pancreas, salivery gland, placenta, mammary gland and testis. Function: GPCR SALPR, also known as Relaxin 3 Receptor 1 (RXFP3), 骋蛋白偶联受体135/松弛素受体3抗体is a G-protein coupled receptor that is one of the physiological targets for relaxin 3, an insulin-like hormone. Activation of GPCR SALPR results in phosphorylation of ERK1/2. GPCR SALPR has been implicated in anxiety and obesity. A role for relaxin 3 and GPCR SALPR in reproductive function through the hypothalamic-pituitary-gonadal (HPG) axis has also been described. Subcellular Location: Cell membrane; 骋蛋白偶联受体135/松弛素受体3抗体Multi-pass membrane protein. Tissue Specificity: Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 51289 Human Entrez Gene: 239336 Mouse Entrez Gene: 294807 Rat Omim: 609445 Human SwissProt: Q9NSD7 Human SwissProt: Q8BGE9 Mouse Unigene: 170146 Human Unigene: 209312 Mouse Unigene: 127658 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骋蛋白偶联受体135/松弛素受体3抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid