孕**受体β（惭笔搁β）抗体
规格：1尘驳/1尘濒
英文名： Progestin Receptor Beta
别名： MPRB; C6orf33; LMPB1; Lysosomal membrane protein in brain 1; Membrane progestin receptor beta; mPR beta; MPRB; PAQR8; Progestin and adipoQ receptor family member 8; Progestin and adipoQ receptor famil
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Progesti
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .
细胞定位：细胞膜
孕**受体β（惭笔搁β）抗体产物介绍：background: The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Five distinct groups, designated Alpha, Beta, Gamma, Delta, comprise the mPR gene family. mPR Alpha, also designated progestin and adipo Theta receptor family member VII (PAQR7), consists of an extracellular N-terminus, an intracellular C-terminus and seven transmembrane domains. mPR Alpha is expressed in ovary, testis,孕**受体β（惭笔搁β）抗体 placenta, uterus and bladder. mPR Beta, or progestin and adipo Theta receptor family member VIII (PAQR8), consists of eight putative transmembrane regions and an intracellular N-terminus that contains a leucine-rich motif. mPR Beta is a 354 amino acid protein expressed in brain and spinal cord. Both mPR Alpha and mPR Beta may be G protein-coupled receptors and may be involved in oocyte maturation. Function: MPRb (Membrane progestin receptor beta) is a steroid membrane receptor and binds progesterone. MPRb may be involved in oocyte maturation. MPRb is an integral membrane protein and is expressed in brain and testis. It belongs to the ADIPOR family. Subcellular Location: Cell Membrane. Multi-pass membrane protein.孕**受体β（惭笔搁β）抗体 Note: Colocalizes with a lysosomal protein cathepsin D. Similarity: Belongs to the ADIPOR family. Database links: Entrez Gene: 85315 Human Entrez Gene: 74229 Mouse Entrez Gene: 316275 Rat Omim: 607780 Human SwissProt: Q8TEZ7 Human SwissProt: Q80ZE5 Mouse SwissProt: Q6AY03 Pig Unigene: 239388 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
孕**受体β（惭笔搁β）抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid