叠贰狈顿4蛋白抗体
规格：1尘驳/1尘濒
英文名： BEND4
别名： BEN domain containing 4; BEN domain containing protein 4; BEN domain-containing protein 4; Bend4; BEND4_HUMAN; CCDC4; Coiled coil domain containing 4; Coiled coil domain containing protein 4; Coiled-c
分子量： 58kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BEND4/CC
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：
叠贰狈顿4蛋白抗体产物介绍：background: BEND4 is a 530 amino acid protein that contains a BEN domain. BEND4 exists as five alternatively spiced isoforms and is considered a complete proteome. BEN domain mediates protein–DNA and protein–protein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND4 gene maps to human chromosome 4p13. Representing approximately 6% of the human genome, chromosome 4 contains nearly叠贰狈顿4蛋白抗体 900 genes. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has 叠贰狈顿4蛋白抗体been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 BEN domain. Database links: UniProtKB/Swiss-Prot: Q6ZU67.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
叠贰狈顿4蛋白抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 肿瘤细胞生物标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid