91蜜桃视频

产物资料

磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体

如果您对该产物感兴趣的话,可以
产物名称: 磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体
产物型号: phospho-DDX5 (Tyr593)
产物展商: 单克隆抗体/多克隆抗体
产物文档: 无相关文档

简单介绍

磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体  的详细介绍

磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体

规格:1尘驳/1尘濒

英文名: phospho-DDX5 (Tyr593)

别名: DDX5 (phospho Y593); DDX5 (phospho Tyr593); p-DDX5 (Y593); p-DDX5 (Tyr593); ATP dependent RNA helicase DDX5; DDX 5; Ddx5; DDX5_HUMAN; DEAD (Asp Glu Ala Asp) box helicase 5; DEAD (Asp Glu Ala Asp) box

分子量: 69kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthesised phosphopeptide derived from human

交叉反应:Human, Mouse, Rat, Cow, Horse, Rabbit,

细胞定位:细胞核

磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体产物介绍:background: p68 RNA helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA helicase activity. p68 RNA helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA helicase increases in serum-induced quiescent cell lines. p68 RNA helicase may function as a coactivator for estrogen receptor alpha. Additionally, p68 RNA helicase associates with transcriptional coactivators CBP and p300. p68 RNA helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA helicase and fibrillarin colocalize to nascent nucleoli. p68 RNA helicase may function as a heterodimer with p72 RNA helicase. Function: RNA-dependent ATPase activity. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. May be involved in pre-mRNA splicing. Subunit: Interacts with BRDT (By similarity). Identified in thespliceosome C complex. Interacts with RBM4; the interaction occursin a RNA-independent manner. Interacts with EIF2C1 and EIF2C2.Interacts with ESR1; the interaction is enhanced by phosphorylationof ESR1 AF-1 domain. Interacts with AR, NCOA1, NCOA2, NCOA3, EP300,CREBBP, POLR2A, TP53, RUNX2 and HDAC1. Self-associates. Interactswith DDX17. [INTERACTION] Q12873:CHD3; NbExp=4; IntAct=EBI-351962, EBI-523590;P45481:Crebbp (xeno); NbExp=3; IntAct=EBI-351962, EBI-296306;Q09472:EP300; NbExp=4; IntAct=EBI-351962, EBI-447295; P03372:ESR1;NbExp=8; IntAct=EBI-351962, EBI-78473; P22087:FBL; NbExp=6;IntAct=EBI-351962, EBI-358318; Q13547:HDAC1; NbExp=4;IntAct=EBI-351962,磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体 EBI-301834; O95983:MBD3; NbExp=4;IntAct=EBI-351962, EBI-1783068; P10085:Myod1 (xeno); NbExp=3;IntAct=EBI-351962, EBI-4405734; P24928:POLR2A; NbExp=3;IntAct=EBI-351962, EBI-295301; Q08775-3:Runx2 (xeno); NbExp=2;IntAct=EBI-351962, EBI-6119991; P04637:TP53; NbExp=3;IntAct=EBI-351962, EBI-366083; P04637-1:TP53; NbExp=2;IntAct=EBI-351962, EBI-3895849; P04637-7:TP53; NbExp=2;IntAct=EBI-351962, EBI-3895873. Subcellular Location: Nucleus. Post-translational modifications: Arg-502 is dimethylated, probably to asymmetricdimethylarginine. Sumoylated; sumoylation, promoted by PIAS1, promotesinteraction with HDAC1 and transcriptional repression activity.磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体Sumoylation also significantly increases stability, and reducespolyubiquitination. Polyubiquitinated, leading to proteasomal degradation. Similarity: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Gene ID: 1655 Database links: Entrez Gene: 1655 Human Entrez Gene: 13207 Mouse Entrez Gene: 287765 Rat Omim: 180630 Human SwissProt: P17844 Human SwissProt: Q61656 Mouse Unigene: 279806 Human Unigene: 220038 Mouse Unigene: 162208 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

磷酸化叁磷酸腺苷依赖解旋酶诲诲虫5抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:发育生物学  神经生物学  信号转导  激酶和磷酸酶  细胞分化  表观遗传学  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


产物留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键础濒迟+厂或颁迟谤濒+贰苍迟别谤发送信息!
2.如有必要,请您留下您的详细联系方式!