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范可尼综合征相关锌指蛋白抗体

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产物名称: 范可尼综合征相关锌指蛋白抗体
产物型号: TZFP/ZNF538
产物展商: 单克隆抗体/多克隆抗体
产物文档: 无相关文档

简单介绍

范可尼综合征相关锌指蛋白抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。范可尼综合征相关锌指蛋白抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


范可尼综合征相关锌指蛋白抗体  的详细介绍

范可尼综合征相关锌指蛋白抗体

规格:1尘驳/1尘濒

英文名: TZFP/ZNF538

别名: FANCC interacting protein; FANCC-interacting protein; Fanconi anemia zinc finger protein; FAXF; FAZF; OTTHUMP00000045790; repressor of GATA; Rog; Testis zinc finger protein; ZBT32_HUMAN; Zbtb32; ZBTB3

分子量: 53kDa

储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human TZFP/ZNF

交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Cat,

细胞定位:细胞核

范可尼综合征相关锌指蛋白抗体产物介绍:Function: DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells. Subunit: Homodimer (via PTB domain). Interacts with the N-terminal of FANCC. Interacts with ZBTB16. Interacts with GATA3 (By similarity). Subcellular Location: Nucleus. Located in nuclear speckles. Tissue Specificity: Predominantly expressed in testis. Some isoforms are ubiquitously expressed. Similarity: Belongs to the krueppel 范可尼综合征相关锌指蛋白抗体C2H2-type zinc-finger protein family. Contains 1 BTB (POZ) domain. Contains 3 C2H2-type zinc fingers. Gene ID: 27033 Database links: Entrez Gene: 27033 Human Entrez Gene: 58206 Mouse Entrez Gene: 688845 Rat Omim: 605859 Human SwissProt: 范可尼综合征相关锌指蛋白抗体Q9Y2Y4 Human SwissProt: Q9JKD9 Mouse Unigene: 99430 Human Unigene: 116789 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

范可尼综合征相关锌指蛋白抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:转录调节因子  锌指蛋白  表观遗传学  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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