锌指蛋白437抗体
规格:1尘驳/1尘濒
英文名: ZBTB2
别名: ZNF437; ZBTB2; ZBTB2_HUMAN; Zinc finger and BTB domain containing 2; Zinc finger and BTB domain-containing protein 2; ZNF437; Zinc finger 437; bA351K16.2; Gm1103; KIAA1483.
分子量: 57kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZBTB2 (4
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核
产锌指蛋白437抗体品介绍:background: The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. ZBTB1 (zinc finger and BTB domain containing 1), also known as KIAA0997, is a 713 amino acid nuclear protein that contains锌指蛋白437抗体 one BTB (POZ) domain and 8 C2H2-type zinc fingers. ZBTB2 is a 514 amino acid nuclear protein that contains one BTB (POZ) domain and 4 C2H2-type zinc fingers. ZBTB25, also known as ZNF46 or KUP, is a 435 amino acid nuclear protein that is expressed mainly in hematopoietic cells and testis and contains one BTB (POZ) domain and 2 C2H2-type zinc fingers. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 BTB 锌指蛋白437抗体(POZ) domain. Contains 4 C2H2-type zinc fingers. Gene ID: 57621 Database links: UniProtKB/Swiss-Prot: Q8N680.1 Entrez Gene: 484036 Dog Entrez Gene: 100060294 Horse Entrez Gene: 57621 Human Entrez Gene: 381990 Mouse Entrez Gene: 308126 Rat SwissPot: Q8N680 Human Unigene: 520073 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白437抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-100 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 细胞周期蛋白 转录调节因子 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid