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硫酯酶超家族成员4抗体

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产物名称: 硫酯酶超家族成员4抗体
产物型号: THEM4
产物展商: 单克隆抗体/多克隆抗体
产物文档: 无相关文档

简单介绍

硫酯酶超家族成员4抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。硫酯酶超家族成员4抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


硫酯酶超家族成员4抗体  的详细介绍

硫酯酶超家族成员4抗体

规格:1尘驳/1尘濒

英文名: THEM4

别名: Acyl CoA thioesterase THEM4; Acyl coenzyme A thioesterase THEM4; C terminal modulator protein; Carboxyl-terminal modulator protein; CTMP; FLJ27206; MGC29636; OTTHUMP00000015248; Them4; THEM4_HUMAN; Th

分子量: 27kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human THEM4

交叉反应:Human, Mouse, Rat,

细胞定位:细胞膜

硫酯酶超家族成员4抗体产物介绍:background: Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq, Jul 2008] Function: According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and硫酯酶超家族成员4抗体 translocation to plasma membrane. Subcellular Location: Cell membrane. Cell projection > ruffle membrane. Cytoplasm. Tissue Specificity: Expressed predominantly in skeletal muscle, testis, uterus, brain and kidney. Down-regulated in glioblastoma or glioma compared to non-neoplastic brain due to promoter hypermethylation. Post-translational modifications: Phosphorylated. Database links: Entrez Gene: 117145 Human Entrez Gene: 75778 Mouse Entrez Gene: 361992 Rat Omim: 606388 Human SwissProt: Q5T1C6 Human SwissProt: Q3UUI3 Mouse SwissProt: Q566R0 Rat Unigene:硫酯酶超家族成员4抗体 164070 Human Unigene: 45092 Mouse Unigene: 12625 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

硫酯酶超家族成员4抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  信号转导  激酶和磷酸酶  结合蛋白  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid




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