负延伸因子颁/顿抗体
规格：1尘驳/1尘濒
英文名： TH1L
别名： HSPC130; Negative elongation factor C/D; NELF C; NELF D; NELF-C/D; NELFC; NELFD; NELFD_HUMAN; TH1; TH1-like protein; TH1L.
分子量： 66kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TH1L
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞核
负延伸因子颁/顿抗体产物介绍：background: The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini. [provided by RefSeq, Jul 2008] Function: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Subcellular 负延伸因子颁/顿抗体Location: Nucleus. Tissue Specificity: Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal and cardiac muscle, adrenal, thyroid, kidney and pancreas. Similarity: Belongs to the NELF-D family. Database links: Entrez Gene: 51497 Human 负延伸因子颁/顿抗体Entrez Gene: 57314 Mouse Omim: 605297 Human SwissProt: Q8IXH7 Human SwissProt: Q922L6 Mouse SwissProt: A5GFY4 Pig Unigene: 517148 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
负延伸因子颁/顿抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid