DNA聚合酶δ 抗体
规格：1尘驳/1尘濒
英文名： DNA polymerase delta
别名： DNA polymerase delta subunit 2; DNA polymerase delta subunit p50; DNA polymerase subunit delta 2; DNA polymerase subunit delta p50; DPOD2_HUMAN; POLD 2; POLD2.
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human DNA poly
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞核
产DNA聚合酶δ 抗体品介绍：background: DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases (1). In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches (2). These exonucleases include the family of DNA polymerases (3). DNA pol α, β, ?, and e are involved in DNA replication and repair (4). DNA pol ? and DNA pol e are multisubunit enzymes, with DNA pol ? consisting of two subunits p125, which interacts with the sliding DNA clamp protein PCNA, and p50 (5). TheDNA聚合酶δ 抗体 nuclear-encoded DNA pol © is the only DNA polymerase required for the replication of the mitochondrial DNA (6). DNA pol Ω is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis (7). DNA pol ? is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks (8). Function: The function of the small subunit is not yet clear. DNA聚合酶δ 抗体Subcellular Location: Nucleus. Similarity: Belongs to the DNA polymerase delta/II small subunit family. Database links: UniProtKB/Swiss-Prot: P49005.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产DNA聚合酶δ 抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid